Pioneering Biology-Informed Psychiatry
HealthyMentis supports clinical decision-making for ADHD and comorbid conditions through neurometabolic patient profiling.
ADHD and comorbid conditions such as depression, anxiety, and fatigue are clinically defined but biologically heterogeneous.
Individuals with similar symptoms may differ substantially in their underlying biology, which can contribute to differences in treatment needs, response, and outcomes.
HealthyMentis translates neurometabolic biology into clinical decision support and treatment design tools.
Biology: The Emerging Dimension In Psychiatry 1
Psychiatric care has traditionally relied on symptoms, clinical interviews, and patient history. While these remain essential, they do not assess the biological heterogeneity that may exist within clinically defined conditions.
Advances in neuroscience and systems biology increasingly suggest that biological factors contribute to symptom presentation and treatment response. Understanding these factors may help support more individualized evaluation and treatment design.
1 Consistent with a broader shift toward biologically informed approaches across neuroscience and medicine. The Lancet Editorial (2026) noted that “Neurology is entering a biologically informed era with unprecedented potential to prevent or delay disease onset and reduce disability.”
How The HealthyMentis
Neurometabolic Assessment Works
From Neurometabolic Biology to Patient Profiles
HealthyMentis combines multi-timepoint dried urine data and symptom information to generate patient-specific neurometabolic profiles.
These profiles are analyzed to identify pathway-level impairments and support patient stratification, individualized treatment design, and longitudinal monitoring.
| 1 | Multi-timepoint biological samplingNon-invasive dried urine samples collected across the day to capture dynamic biological activity. |
| 2 | Neurometabolic pathway analysisIdentification of pathway-level impairments across interconnected neurometabolic pathways. |
| 3 | Patient profile generationIntegration of biological measurements with questionnaire-based symptom data. |
| 4 | Biology-informed treatment designIdentification of biologically distinct patient profiles that support patient stratification and individualized treatment design. |
One Platform. Two Applications.
HealthyMentis applies its neurometabolic intelligence platform in two settings:
clinical research collaborations and wellness assessments for individuals.
For Clinicians and Researchers
HealthyMentis collaborates with clinicians and researchers in studies to evaluate the clinical utility of neurometabolic patient profiling.
These collaborations are designed to generate evidence supporting the development of a biology-informed Clinical Decision Support and Therapy Optimization (CDS/TxO) platform.
For Individuals
The neurometabolic assessment provides personalized biological insights that may support a deeper understanding of mental health, resilience, and individual biological variability.
Available today as a wellness-based assessment for informational purposes.
